Computational structural biology is a mature field of research whose contribution to life sciences is becoming increasingly more appreciated. The aim of this course is to provide a solid basis of computational structural biology methods, with an emphasis on practical protein modelling and simulation, to interested MSc and PhD students in the life sciences. Further, given the lack of emphasis on practical computational research in MSc and PhD courses, this course is designed to have a smooth learning curve regarding the GNU/Linux environment and its command-line interface. By the end of the course, the students are expected to master the three major computational structural biology methods – homology modelling, molecular dynamics, and protein docking – not only from a user perspective but also from a theoretical standpoint.
The course is scheduled to last two-weeks with theoretical lectures (including some exercises) in the morning (9:00-12:00) and practical sessions in the afternoon (13:15–17:00). The students are required to summarize the results of the computer practicals by writing a short article in the form of a communication for the Journal of the American Chemical Society. The last 2 days of the course are reserved for a guest lecture giving an industry perspective to the topic, the article writing, self study and a final exam. The first afternoon is devoted to the installation of the material and a short crash-course on GNU/Linux and the command-line interface.
Via Osiris student.